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Application Notes – Human health

Application Note 013: The Bio-VOC – A low-cost, simple device for biological monitoring of VOCs in breath
This Application Note describes an easy-to-use device for capturing the volatile organic compounds (VOCs) from breath on sorbent-packed thermal desorption tubes. Examples are provided of how this approach can be applied to a range of health-related applications, including clinical diagnosis and personal exposure monitoring.
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Application Note 018: Determination of nitrous oxide using TD–GC
This Application Note describes the development of a thermal desorption (TD) method for the determination of the anaesthetic nitrous oxide, sampled both passively and by breath sampling using Markes’ Bio-VOC. The personal exposure of midwives was monitored using tubes packed with zeolite molecular sieves, and conditions adapted to minimise introduction of water into the analytical system.
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Application Note 041: Analysis of the residual solvent dimethyl sulfoxide in a drug precursor
This Application Note describes the development of a direct thermal desorption method to analyse residual dimethyl sulfoxide in a drug precursor. An excellent recovery is demonstrated, with less than 3% carryover upon repeat desorption of the same sample.
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Application Note 132: Monitoring VOC emissions from respiratory medical devices in accordance with the new ISO 18562 international standard
This Application Note describes the monitoring of potentially harmful volatile and semi-volatile organic compounds (VOCs and SVOCs) emitted from respiratory medical devices, in accordance with the recently-released ISO 18562 standard. The sampling protocol involves passing the air stream through the medical device and onto a sorbent-packed tube, followed by automated analysis by well-established and reliable TD–GC–MS protocols. Emissions from two sets of face-mask supply tubing and three nasal cannulas were compared, and all were found to emit VOCs, with emission levels being relatively high in the first 24 hours of use.
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UK
UK
Markes International Ltd
Gwaun Elai Medi-Science Campus
Llantrisant
RCT
CF72 8XL, UK
Tel: +44 (0)1443 230935
Germany
Germany
Markes International GmbH
Schleussnerstrasse 42
D-63263 Neu-Isenburg
Frankfurt
Germany
Tel: +49 (0)6102 8825569
USA (West)
USA
Markes International, Inc
2355 Gold Meadow Way
Gold River
California 95670
USA
Tel: 866-483-5684 (toll-free)
Part of Schauenburg International
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