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Enhancing the sensitivity of extraction for the detection of nicotine in complex samples
Case study
Categories: Case study Sample extraction, solids and liquids Environmental High-capacity sorptive extraction Tobacco & e-cigarettes

Enhancing the sensitivity of extraction for the detection of nicotine in complex samples

Technical University of Crete, Greece

Enhancing the sensitivity of extraction for the detection of nicotine in complex samples – Technical University of Crete

Nicotine is considered a so-called ‘emerging lifestyle contaminant’. Professor Elefteria Psillakis at the Technical University of Crete, Greece, used HiSorb™ sample probes to improve the sensitivity of her extraction technique to enable the detection of low levels of nicotine among 4000 compounds.

  • Customer: Technical University of Crete, Greece
  • Application: VOCs from the degradation
    of nicotine leachates from cigarettes
  • Challenge: To improve the sensitivity of the extraction technique to enable identification of
    1 ppm of nicotine in complex matrices
  • Solution: Enhancing the sensitivity of high-capacity sorptive extraction by immersing HiSorb probes in samples
  • Results: Enhanced sensitivity to enable detection of up to 1 ppm of nicotine among 4000 compounds

HiSorb did amazingly well. We were able to monitor the degradation of nicotine in a complex matrix down to a concentration of 1 ppm using conventional GC–MS.

Elefteria Psillakis

Professor of water chemistry, Technical University of Crete, Greece

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Enhancing the sensitivity of extraction for the detection of nicotine in complex samples