Innovative Technology For Trace Organic Analysis
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Sample screening made easy with ChromCompare

Integral to the TOF-DS software package is the innovative ChromCompare® module. ChromCompare saves time and effort when comparing GC–MS profiles and offers two major advantages:

  • Automated and objective fingerprinting of complex profiles, e.g. for quality control or data classification.

  • Fast and reliable screening of large numbers of chromatograms for indicative target compounds.

At-a-glance visualisation of key components

ChromCompare distils the information-rich chromatographic data sets generated by BenchTOF into line chromatograms or ‘H-Plots’, in which the bar heights are proportional to the peak areas of target components. H-Plots are independent of retention time and can be displayed by compound type or any other user-selected parameter.

Simple and objective comparison of samples

Pairs of H-Plots are compared/processed using statistically-defensible algorithms, generating a match factor that removes issues of subjective judgement or operator skill from the entire analysis. Match factors from multiple pair-wise comparisons can be displayed in a matrix to aid rapid identification of anomalous samples.

Key advantages of ChromCompare include:

  • The time-independent H-plot display simplifies data review and allows data to be included from multiple methods and systems, and from libraries of historical reference data.

  • Statistically-robust, numerical match factors provide an objective comparison of complex chromatograms.

  • Critical compounds can be weighted to increase their significance in the matching process, ensuring minor but significant differences are not overlooked.

  • Sample batches can be ‘averaged’ into a single H-plot to account for natural sample variation, thus eliminating false negatives and minimising false positives.

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UK
UK
Markes International Ltd
Gwaun Elai Medi-Science Campus
Llantrisant
RCT
CF72 8XL, UK
Tel: +44 (0)1443 230935
USA (East)
USA (East)
Markes International, Inc
11126-D Kenwood Road
Cincinnati
Ohio 45242
USA
Tel: 866-483-5684 (toll-free)
USA (West)
USA (West)
Markes International, Inc
2355 Gold Meadow Way
Gold River
California 95670
USA
Tel: 866-483-5684 (toll-free)
Germany
Germany
Markes International GmbH
Schleussnerstrasse 42
D-63263 Neu-Isenburg
Frankfurt
Germany
Tel: +49 (0)6102 8825569
Part of Schauenburg International
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